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deta nonoate (MedChemExpress)

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MedChemExpress deta nonoate
Deta Nonoate, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 14 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/deta+nonoate/DETA+NONOate/pm42394282-49-46-49
Average 94 stars, based on 14 article reviews

deta nonoate - by Bioz Stars, 2026-09

94/100 stars

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Inhibition:

Article Title: iNOS/NO-Induced autophagy primes PANoptosis as the central driver of streptococcal toxic shock-like syndrome in zoonotic Streptococcus suis infection.
Article Snippet: For immunofluorescence assays, the following antibodies and reagents were applied: anti-F4/80 (A27257, ABclonal), antiASC (AG-25B-0006, AdipoGen, San Diego, USA), anti-caspase-8 (YM3377, Immunoway, California, USA), anti-RIPK3 (17563-1-AP, Proteintech, Wuhan, China), 488 nm Fluorophore-Labeled Tyramide (YS0007, Immunoway), 594 nm FluorophoreLabeled Tyramide (YS0010, Immunoway), 680 nm Fluorophore-Labeled Tyramide (YS0012, Immunoway). .. In inhibition assays, the following chemical inhibitors were utilized: Z-IETD-FMK (HY-101297, MedChemExpress, New Jersey, USA), VX-765 (HY13205, MedChemExpress), GSK-872 (HY-101872, MedChemExpress), NH4Cl (ST2030, Beyotime Biotechnology, Shanghai, China), Bafilomycin A1 (S1413, Selleck, Texas, USA.), chloroquine (S4157, Selleck), 1400W (HY-18731, MedChemExpress), and Z-VAD-FMK (HY-16658B, MedChemExpress), Rapamycin (HY-10219, MedChemExpress), DETA NONOate (HY-136278, MedChemExpress). ..

Staining:

Article Title: Natural killer cell dysfunction drives keloid pathogenesis.
Article Snippet: Mitochondrial reactive oxygen species assay After stimulating NK cells with IFN-β (10 ng/mL) for 7 days, the mitoSOX Green reagent (Invitrogen, M36005) was dissolved in 10 μL of N,N-Dimethylformamide (Aladdin, D111999-100mL) to prepare a 1 mM stock solution. .. The cells were stained with 1 μM mitoSOX Green reagent at 37◦C under 5% CO2 for 30 min. For the negative control, cells were treated with 2 mg/mL DETA NONOate (MedChemExpress, HY-136278) at 37◦C with 5% CO2 for 30 min. .. The positive control was established by incubating cells with 30 μM MitoPQ (MedChemExpress, HY-130278) under the same conditions for 18 h. All samples were washed three times with PBS and analyzed using a flow cytometer. scRNA-seq library preparation Single-cell RNA-seq libraries were prepared using the SeekOne DD Single Cell 5′ library preparation kit (SeekGene, K00501).

Negative Control:

other:

Article Title: Nitric oxide facilitates the S‐nitrosylation and deubiquitination of Notch1 protein to maintain cancer stem cells in human NSCLC
Article Snippet: L‐NAME, 1400 W 2HCl and S‐Nitrosoglutathione (GSNO) was purchased from Selleck (L‐NAME, S2877; 1400 W, S8337; GSNO, E4443) and DETA NONOate, Mitomycin C and proteasome inhibitor MG132 were from MCE (DETA NONOate, HY‐136278; Mitomycin C, HY‐13316; MG132, HY‐13259).

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$(A,B) Gene maps of two of the most enriched regions in Group B genomes compared with Group A. The region shown in (A) appears to be a defense island. The region shown in (B) contains an operon carrying genes annotated as a putative nitroreductase, an iron-sulfur binding enzyme of unknown function, and a putative glutathione peroxidase. Genes are colored by their log enrichment in Group B genomes, based on a logistic regression model accounting for genome size and MAG status. The peroxidase gene in (B) does not appear enriched because another copy of this gene family appears elsewhere in the core E. lenta genome. Maps of these regions with additional genomic context are included in . (C) Comparison of the region shown in (B) with homologous regions identified in other Eggerthellaceae and in representatives of class Clostridia. The region is found widely, though not universally, in other Eggerthellaceae , and is also common in Clostridia. Homologous regions were identified and used to construct the associated gene tree using the tool fast.genomics . The region found in E. lenta Group B is labeled in bold. The phylogenetic tree is based on the nitroreductase gene amino acid sequences. (D) Differences in growth inhibition by nitric oxide in Group A and B E. lenta. Isolates ( n= 5 from each group) were inoculated into rich media containing initial 64 or 128 µM concentrations of the nitric oxide donor diethylamine NONOate (Wilcoxon rank-sum test). The y -axis represents the fraction of the maximum absorbance reached by that strain in control media.$

Journal: bioRxiv

Article Title: A widespread gut bacterial lineage distinguished by redox metabolism and phage defense

doi: 10.64898/2026.03.31.715625

Figure Lengend Snippet: (A,B) Gene maps of two of the most enriched regions in Group B genomes compared with Group A. The region shown in (A) appears to be a defense island. The region shown in (B) contains an operon carrying genes annotated as a putative nitroreductase, an iron-sulfur binding enzyme of unknown function, and a putative glutathione peroxidase. Genes are colored by their log enrichment in Group B genomes, based on a logistic regression model accounting for genome size and MAG status. The peroxidase gene in (B) does not appear enriched because another copy of this gene family appears elsewhere in the core E. lenta genome. Maps of these regions with additional genomic context are included in . (C) Comparison of the region shown in (B) with homologous regions identified in other Eggerthellaceae and in representatives of class Clostridia. The region is found widely, though not universally, in other Eggerthellaceae , and is also common in Clostridia. Homologous regions were identified and used to construct the associated gene tree using the tool fast.genomics . The region found in E. lenta Group B is labeled in bold. The phylogenetic tree is based on the nitroreductase gene amino acid sequences. (D) Differences in growth inhibition by nitric oxide in Group A and B E. lenta. Isolates ( n= 5 from each group) were inoculated into rich media containing initial 64 or 128 µM concentrations of the nitric oxide donor diethylamine NONOate (Wilcoxon rank-sum test). The y -axis represents the fraction of the maximum absorbance reached by that strain in control media.

Article Snippet: A 5 mM stock solution of diethylamine NONOate (DETA NONOate, MedChemExpress #HY-136278) was prepared in ultrapure water, filter-sterilized with a 0.22 μM syringe filter, and transferred into 0.5 mL aliquots on ice.

Techniques: Binding Assay, Comparison, Construct, Labeling, Inhibition, Control